About me

Computational biologist with over 20 years of experience analyzing complex biological data and deploying scalable infrastructure. Originally trained in molecular biology and genetics at Eötvös Loránd University, I transitioned to computational biology during my Master’s studies and subsequently earned a PhD in Classical and Molecular Genetics, focusing on the evolutionary conservation of gene expression regulation. My career spans high-impact roles across agricultural biotechnology, cancer genomics, and molecular diagnostics, where I specialized in engineering end-to-end bioinformatics pipelines, developing novel analytical tools, and bridging the gap between dry-lab and wet-lab teams. Across these roles, I handled multi-terabyte datasets, analyzed hundreds of patient samples, and frequently managed research projects.

Currently operating as an independent consultant, I partner with biotech startups, academic laboratories, and independent researchers to translate raw sequencing data into biological discoveries, utilizing R, Python, Snakemake, and cloud infrastructure (AWS/GCP). To complement my deep expertise in genomics and transcriptomics, I also hold a Master’s in Human Ecology. This unique combination allows me to apply systems-level thinking — integrating sociology, ecology, and data science — to complex biological problems, making me a highly adaptable partner for projects requiring both granular genetic analysis and macro-scale environmental or ecological context.

Endre Sebestyén

Available for new projects

Available for consulting engagements, pipeline development, or workflow auditing — let’s turn your next-generation sequencing results into actionable insights.

Let’s discuss your project

Experience

  1. Bioinformatics Consultant

    December 2020 – Present

    The Bioinformatics CRO · Orlando, Florida, US

    Partnering with diverse clients to translate next-generation sequencing (NGS) data into biological insights, specializing in custom genomics and transcriptomics pipelines.

  2. Bioinformatics Group Leader

    September 2018 – December 2021

    Semmelweis University · Budapest, HU

    Directed genomics and molecular diagnostics research initiatives, managed a dedicated bioinformatics team, mentored junior scientists, and instructed university-level data science courses.

  3. Postdoctoral researcher

    September 2015 – August 2018

    IFOM-ETS · Milan, IT

    Analyzed complex genomic datasets to uncover mechanisms driving cancer and rare diseases; engineered novel biostatistical methods and software tools to model chromatin architecture.

  4. Postdoctoral researcher

    February 2012 – August 2015

    GRIB-UPF · Barcelona, ES

    Processed large-scale cancer genomic and transcriptomic cohorts, developing a novel computational framework to detect transcript isoform and alternative splicing switches across tumor samples.

  5. Bioinformatician

    January 2006 – January 2012

    Agricultural Research Institute of the Hungarian Academy of Sciences · Martonvásár, HU

    Spearheaded bioinformatics, biostatistics, and data visualization workflows supporting agricultural genomics and plant genetics. Advanced agritech initiatives through custom database integration and multi-omics analysis of non-model organisms.

  6. PhD Candidate

    September 2003 – August 2006

    Agricultural Biotechnology Center · Gödöllő, HU

    Executed agricultural bioinformatics and biostatistical analyses, building and managing specialized databases and web-accessible tools to support high-throughput genomics research.

Education

  1. MA in Human Ecology

    2021 – 2023

    Eötvös Loránd University

    Research focus: modeling long-term landscape transformation in the Middle-Ipoly region by integrating quantitative GIS and meteorological datasets with qualitative interviews and historical source analysis.

  2. PhD in Classical and Molecular Genetics

    2003 – 2006

    Eötvös Loránd University

    Research focus: development of DoOP and DoOPSearch, web-based eukaryotic promoter motif search and enrichment tools for comparative genomics.

  3. MSc in Biology

    1998 – 2003

    Eötvös Loránd University

    Research focus: analysis of the evolutionary conservation of eukaryotic transcription factor binding sites and promoter regions.

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